Department of Translational Genomics Lab Pages, Student Resources, and Web Applications

News

Javed Khan to Present in Translational Genomics Virtual Distinguished Lecture Series

   

Exploration and Targeting the Epigenome of Fusion Positive Rhabdomyosarcoma

Javed Khan, MD
Deputy Chief Genetics Branch and Senior Investigator
Oncogenomics Section
Center for Cancer Research CCR

Tuesday, September 29, 2020
11:00 am – 12:00 pm
Webinar Registration

  • Rhabdomyosarcoma (RMS) genomics
  • Reprograming of the epigenome by PAX3-FOXO1
  • Hijacking of the FOXO1 enhancer by PAX3-FOXO1 translocation
  • Defining the core regulatory circuitry of fusion positive RMS
  • Drugging the undruggable: inhibitors of PAX3-FOXO1 activity
    • BRD4i
    • HDACi
  seminar flyer and contact information
✔   register to receive meeting password

Melissa Boneta Davis to Present in Translational Genomics Virtual Distinguished Lecture Series

   

Exploration and Targeting the Epigenome of Fusion Positive Rhabdomyosarcoma

Melissa Boneta Davis, PhD
Assistant Professor of cell and Developmental Biology in Surgery
Scientific Director of the International Center for the Study of Breast Cancer Subtypes
Weill Cornell Medicine

Tuesday, October 10, 2020
11:00 am – 12:00 pm
Webinar Registration

The Davis Lab current research program is focused on identification of biological mechanisms of racial disparities in cancer risk and clinical outcomes of cancer diagnoses. The Davis lab has produced findings that show unique genetic signatures, in both breast and prostate tumors of African and African American patients, enriched for mechanisms that correlate with aggressive tumor progression and tumor immunology. These findings generate novel opportunities for precision medicine applications in minority populations. She will present findings emerging from her breast cancer research, where she has identified that African-associated gene expression signatures and the allele of a gene named DARC (ACKR1) is linked to the tumor-specific immune/inflammatory response.

  seminar flyer and contact information
✔   register to receive meeting password

Department Chair Dr. Carpten Kicked Off Translational Genomics Virtual Distinguished Lecture Series

   

USC Translational Genomics:
Accelerating Improvements in Healthcare at USC KSOM through Intentional Integration between Basic Discovery Research and Clinical Science

John D. Carpten, PhD
Professor, USC Department of Urology
Chair, USC Department of Translational Genomics
Director, USC Institute for Translational Genomics
Director, USC Molecular Genomics Core
Co-Leader, Norris Comprehensive Cancer Center

Tuesday, August 18, 2020
11:00 am – 12:00 pm
Webinar

In 2016, the USC Department of Translational Genomics was created under the leadership of the founding chair John Carpten, PhD with co-leadership by Vice Chair Dr. David Craig.  The mission of USC Translational Genomics is to help the Keck School of Medicine realize its full potential in improving patient outcomes through the intentional integration of basic and clinical research.  The foundational components of our department include genome science and biomedical informatics.  The department currently includes eight faculty members dedicated to scholarship, teaching and education, and service to the community.  The department hosts several major grants and is focused on translating genomic discoveries into new knowledge that may someday have clinical application.  The department also contributes to the educational mission of the university through its master’s degree programs in Translational Biotechnology and Translational Biomedical Informatics.   Diversity is also a major component of our departmental foundation, including being among the world leaders in research studies that aim to understand the relationship between population differences and disease incidence and outcomes, and in our intentional goals for biomedical workforce diversity.

  seminar flyer and contact information
  presentation slides:      Deck 1           Deck 2